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Greater regional cortical gray matter thickness in obsessive-compulsive disorder
Source: NeuroReport 2008 Oct;19(15):1551-1555.
Author: Narayan VM, Narr KL, Phillips OR, Thompson PM, Toga AW, Szeszko PR
PubMed ID: 18797315
Abstract:
Earlier studies are inconsistent regarding the structural basis of obsessive-compulsive disorder (OCD), and few studies have investigated whether patients with OCD have cortical thickness abnormalities compared with healthy volunteers. Using magnetic resonance imaging we compared regional di¡erences in cortical thickness among 21 patients with OCD and 21 demographically matched healthy volunteers. Our ¢ndings indicate that the right inferior frontal cortex and posterior middle temporal gyrus are thicker in patients with OCD compared with healthy controls, which may contribute to response inhibition de¢cits and other aspects of phenomenology related to the disorder.
Source: NeuroReport 2008 Oct;19(15):1551-1555.
Author: Narayan VM, Narr KL, Phillips OR, Thompson PM, Toga AW, Szeszko PR
PubMed ID: 18797315
Abstract:
Earlier studies are inconsistent regarding the structural basis of obsessive-compulsive disorder (OCD), and few studies have investigated whether patients with OCD have cortical thickness abnormalities compared with healthy volunteers. Using magnetic resonance imaging we compared regional di¡erences in cortical thickness among 21 patients with OCD and 21 demographically matched healthy volunteers. Our ¢ndings indicate that the right inferior frontal cortex and posterior middle temporal gyrus are thicker in patients with OCD compared with healthy controls, which may contribute to response inhibition de¢cits and other aspects of phenomenology related to the disorder.