Publications
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Gender effects on callosal thickness in scaled
and unscaled space
Source: NeuroReport 2006 Jul;17(11):1103-1106.
Author: Luders E, Narr KL, Zaidel E, Thompson PM, Toga AW.
PubMed ID: 16837835
Abstract:
Some empirical data suggest that sexual dimorphisms in callosal morphology exist, but ¢ndings are not consistently replicated across laboratories.We applied novel computational surface-based methods to encode callosal thickness at high spatial resolution. We further examined whether callosal thickness and related gender e¡ects are in£uenced by brain size adjustments achieved through data scaling. Signi¢cant gender di¡erences were absent in scaled data, and women showed no regional thickness increases comparedwithmen (in either scaled or unscaled data). In unscaled data, men exhibited signi¢cantly greater callosal thickness in a number of regions that may be attributable to larger brain dimensions in men. Alternatively, given their regional speci¢city, the observed di¡erences in unscaled callosal thickness may contribute to gender-speci¢c cognition and behavior.
Source: NeuroReport 2006 Jul;17(11):1103-1106.
Author: Luders E, Narr KL, Zaidel E, Thompson PM, Toga AW.
PubMed ID: 16837835
Abstract:
Some empirical data suggest that sexual dimorphisms in callosal morphology exist, but ¢ndings are not consistently replicated across laboratories.We applied novel computational surface-based methods to encode callosal thickness at high spatial resolution. We further examined whether callosal thickness and related gender e¡ects are in£uenced by brain size adjustments achieved through data scaling. Signi¢cant gender di¡erences were absent in scaled data, and women showed no regional thickness increases comparedwithmen (in either scaled or unscaled data). In unscaled data, men exhibited signi¢cantly greater callosal thickness in a number of regions that may be attributable to larger brain dimensions in men. Alternatively, given their regional speci¢city, the observed di¡erences in unscaled callosal thickness may contribute to gender-speci¢c cognition and behavior.