Publications
Text queries can be conducted by Author, Title, or Keyword.
Optical Imaging in Animals and Humans
Source: 2003;.
Author: Toga AW, Pouratian N, Sheth SA, Guiou M, Nemoto M.
Abstract:
Optical imaging of intrinsic signals maps the brain by measuring intrinsic activity-related changes in tissue reflectance. Functional physiological changes such as increases in blood volume, hemoglobin oxymetry changes, and light scattering changes result in intrinsic tissue reflectance changes that are exploited to map functional brain activity. Intrinsic optical changes have been reported in rodents (Masino et al. 1993; Narayan et al. 1994), cats (Bonhoeffer and Grinvald 1991; Frostig et al. 1990), monkeys (Grinvald et al. 1991; Ts'o et al. 1990), and humans (Haglund et al. 1992; Toga et al. 1995a). This mini-review provides a brief overview of our recent work, a description of our methods and how they can be applied in animal models and humans, as well as potential future applications. We survey an array of optical imaging techniques and applications including discussions of intrinsic signal etiology, results from various animal models, recent advances in optical imaging in humans, and integrating optical imaging with other functional imaging techniques to better understand the etiology of functional brain mapping signals.
Source: 2003;.
Author: Toga AW, Pouratian N, Sheth SA, Guiou M, Nemoto M.
Abstract:
Optical imaging of intrinsic signals maps the brain by measuring intrinsic activity-related changes in tissue reflectance. Functional physiological changes such as increases in blood volume, hemoglobin oxymetry changes, and light scattering changes result in intrinsic tissue reflectance changes that are exploited to map functional brain activity. Intrinsic optical changes have been reported in rodents (Masino et al. 1993; Narayan et al. 1994), cats (Bonhoeffer and Grinvald 1991; Frostig et al. 1990), monkeys (Grinvald et al. 1991; Ts'o et al. 1990), and humans (Haglund et al. 1992; Toga et al. 1995a). This mini-review provides a brief overview of our recent work, a description of our methods and how they can be applied in animal models and humans, as well as potential future applications. We survey an array of optical imaging techniques and applications including discussions of intrinsic signal etiology, results from various animal models, recent advances in optical imaging in humans, and integrating optical imaging with other functional imaging techniques to better understand the etiology of functional brain mapping signals.