Abstract:
We studied a 69-year-old man with multiple brain infarcts who died
8 days after being studied with positron emission tomography and (F-18)-
fluorodeoxyglucose. Metabolic abnormalities were greater than structural
changes in size and extent. They were found in areas with no gross
pathologic abnormalities. Remote metabolic effects were attributed both
to degeneration of fiber tracts with disconnection of remote structures,
as demonstrated by hypometabolism in the left frontal cortex associated
with an infarct in the genu of the left internal capsule, and to
microscopic infarcts not apparent on gross examination but manifested as
hypometabolic regions