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Lateralized lexical decision in schizophrenia: hemispheric specialization and interhemispheric lexicality priming
Source: Journal of Abnormal Psychology 2003 Nov;112(4):623-632.
Author: Narr KL, Green MF, Capetillo-Cunliffe L, Toga AW, Zaidel E.
PubMed ID: 14674874
Abstract:
Reports of left hemisphere dysfunction and abnormal interhemispheric transfer in schizophrenia are mixed and have not been assessed previously using a unified paradigm. A lateralized lexical decision task was administered to male, right-handed schizophrenia patients (n = 34) and controls (n = 20). Word or pronounceable nonword targets and distractors were presented tachistoscopically to each hemifield. Analyses of variance assessed group differences in lexical hemispheric specialization and interhemispheric transfer. Both patients and controls exhibited left hemispheric superiority for lexical processing. Patients showed selective-interhemispheric lexicality priming where accuracy was better when the lexical status of the target and distractor stimuli were congruent. Results suggest that schizophrenia is associated with increased interhemispheric automatic information transfer rather than with changed hemispheric specialization for language.
Source: Journal of Abnormal Psychology 2003 Nov;112(4):623-632.
Author: Narr KL, Green MF, Capetillo-Cunliffe L, Toga AW, Zaidel E.
PubMed ID: 14674874
Abstract:
Reports of left hemisphere dysfunction and abnormal interhemispheric transfer in schizophrenia are mixed and have not been assessed previously using a unified paradigm. A lateralized lexical decision task was administered to male, right-handed schizophrenia patients (n = 34) and controls (n = 20). Word or pronounceable nonword targets and distractors were presented tachistoscopically to each hemifield. Analyses of variance assessed group differences in lexical hemispheric specialization and interhemispheric transfer. Both patients and controls exhibited left hemispheric superiority for lexical processing. Patients showed selective-interhemispheric lexicality priming where accuracy was better when the lexical status of the target and distractor stimuli were congruent. Results suggest that schizophrenia is associated with increased interhemispheric automatic information transfer rather than with changed hemispheric specialization for language.