Publications
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Bilateral fetal grafts for Parkinson's disease: 22 months'
results
Source: Stereotact Funct Neurosurg 1992;58(1-4):84-87.
Author: Iacono RP;Tang ZS;Mazziotta JC;Grafton S;Hoehn M
PubMed ID: 1439354
Abstract:
Five patients with severe Parkinson's disease underwent bilateral multiple graft implants of nondissociated fetal mesodiencephalic tissues. Graft implantation was performed in China following CT-guided stereotactic placement of a novel delivery system. Follow-up has demonstrated substantially reduced levodopa requirements and clinical improvements of motor, postural functions and reduction of freezing and on-off phenomenon. PET utilizing [18F]-dopa, at 14 months in the first case, suggested graft-induced restoration of dopaminergic transmission in the striatum
Source: Stereotact Funct Neurosurg 1992;58(1-4):84-87.
Author: Iacono RP;Tang ZS;Mazziotta JC;Grafton S;Hoehn M
PubMed ID: 1439354
Abstract:
Five patients with severe Parkinson's disease underwent bilateral multiple graft implants of nondissociated fetal mesodiencephalic tissues. Graft implantation was performed in China following CT-guided stereotactic placement of a novel delivery system. Follow-up has demonstrated substantially reduced levodopa requirements and clinical improvements of motor, postural functions and reduction of freezing and on-off phenomenon. PET utilizing [18F]-dopa, at 14 months in the first case, suggested graft-induced restoration of dopaminergic transmission in the striatum