at the University of Southern California

Learn more about the INI’s research by viewing our 2019 annual report.

The USC Mary and Mark Stevens Neuroimaging and Informatics Institute applies innovative imaging and information technologies to the study of the brain. We collect and analyze imaging, genetics, clinical, and behavioral data to better understand the brain’s role in human health, disease, and changes across the lifespan.

The INI houses the Laboratory of Neuro Imaging, along with the Imaging Genetics Center, Center for Image Acquisition, and Center for Integrative Connectomics. Explore the links below to learn more.

Our Mission

Mapping the brain -

We’re using advanced imaging technologies and techniques to create the world’s most detailed map of connections inside the brain.

Understanding disease -

By combining data from clinical, behavioral, genetics, and imaging studies, we seek to answer key questions about what can go wrong in the brain and learn how to prevent or reverse the damage.

Developing shareable tools -

We design our experimental protocols, software, and analytical tools to be shared with the larger research community. Our team has also helped revolutionize data sharing by creating public archives that facilitate worldwide collaboration.

Training new leaders -

Our one-year M.S. program in Neuroimaging and Informatics prepares scientists for rewarding careers in biomedicine. We also offer a series of workshops, seminars, and online educational tools to train researchers in the latest imaging and informatics technology.


Originally established as a research laboratory at Washington University School of Medicine in St. Louis, LONI has more than three decades of expertise in studying the brain.

Research Focus

LONI uses cutting-edge imaging technology, including Siemens Magnetom Terra 7T and Prisma 3T MRI scanners, to collect images of the brain. We look at the structure, function, and connectivity of the human brain in healthy individuals across the lifespan. Our researchers also study patients with neurodegenerative disorders such as Alzheimer’s and Parkinson’s Diseases and psychiatric disorders such as schizophrenia, depression, and ADHD. We aim to find biomarkers that can be used to identify at-risk populations. By developing a more comprehensive picture of the brain, we can contribute to finding treatments and cures for some of the world’s most debilitating disorders.

Informatics is an interdisciplinary field that uses applied information technology to better understand and use data. By applying sophisticated mathematical and computational tools, along with new methods of visualization, informatics seeks to glean additional insights from the vast amounts of data scientists collect. We apply informatics to biomedical research, specifically focusing on ways it can help us understand the human brain in health and disease.

We’ve constructed 3D brain atlases based on our research, which represent some of the most details neurological maps in existence. Multiple LONI projects, including our Image and Data Archive, facilitate data sharing among thousands of researchers worldwide. LONI is a key partner in many unique national and international collaborations. We’re pooling our best resources with those of other experts to speed up the pace of discovery in the field.

Learn more about our research
Read more about LONI's collaboration with Formal Collaborators

Stevens Hall of Neuroimaging features state-of-the-art imaging and data archival technology, as well as modern computer workstations and conference spaces to accommodate our multidisciplinary research team and staff.

Facility Highlights
  • Magnetic Resonance Imaging Scanners
    • Siemens Magnetom Prisma 3 Tesla
    • Siemens Magnetom Terra 7 Tesla
    • Learn more
  • Noninvasive Brain Stimulation Center
    • Transcranial Magnetic Stimulation
    • Transcranial Electrical Stimulation
    • Transcranial Alternating Current Stimulation
    • Transcranial Random Noise Stimulation
  • Data Immersive Visualization Environment (DIVE)
    • 50-seat, high defination interactive theater designed to facilitate visualization, discussion, and training
  • Data Center